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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRY1
All Species:
37.58
Human Site:
Y428
Identified Species:
63.59
UniProt:
Q16526
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16526
NP_004066.1
586
66395
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Chimpanzee
Pan troglodytes
XP_509339
586
66344
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Rhesus Macaque
Macaca mulatta
XP_001100653
586
66450
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Dog
Lupus familis
XP_531757
606
68237
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P97784
606
67983
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Rat
Rattus norvegicus
Q32Q86
588
66212
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508613
577
65001
Y389
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Chicken
Gallus gallus
Q8QG61
621
69654
Y428
R
T
D
P
N
G
D
Y
I
R
R
Y
L
P
V
Frog
Xenopus laevis
Q75WS4
523
60626
K371
N
V
A
S
F
L
T
K
D
L
G
I
D
W
R
Zebra Danio
Brachydanio rerio
Q4KML2
520
59903
T369
Q
N
V
A
S
F
L
T
K
D
L
G
L
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77059
542
62494
T383
L
H
H
T
L
R
N
T
V
A
T
F
L
T
R
Honey Bee
Apis mellifera
NP_001077099
570
65246
L417
N
A
G
M
W
M
W
L
S
C
S
S
F
F
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785873
516
59965
L364
A
I
M
T
Q
L
R
L
E
G
W
I
H
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96524
612
69439
Y429
K
Y
D
P
E
G
E
Y
I
R
Q
W
L
P
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
95.3
N.A.
93.5
96.2
N.A.
85.3
87.5
25.7
25
N.A.
37.2
65.3
N.A.
59.5
Protein Similarity:
100
100
99.6
95.8
N.A.
94.7
97.7
N.A.
89.2
92.1
43.5
42.3
N.A.
53.7
78.5
N.A.
70.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
6.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
20
N.A.
26.6
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
65
0
0
0
58
0
8
8
0
0
8
8
0
% D
% Glu:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
8
8
8
0
% F
% Gly:
0
0
8
0
0
65
0
0
0
8
8
8
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
65
0
0
15
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
8
15
8
15
0
8
8
0
79
0
8
% L
% Met:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
8
0
0
58
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
65
0
0
0
0
0
0
0
0
0
72
0
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% Q
% Arg:
58
0
0
0
0
8
8
0
0
65
58
0
0
0
15
% R
% Ser:
0
0
0
8
8
0
0
0
8
0
8
8
0
0
0
% S
% Thr:
0
58
0
15
0
0
8
15
0
0
8
0
0
8
0
% T
% Val:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
58
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
8
8
0
8
8
% W
% Tyr:
0
8
0
0
0
0
0
65
0
0
0
58
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _